Glucosamine, Chondroitin & MSM

Glucosamine, Chondroitin & MSM

$24.90 (MRSP)

Life Vitamins Glucosamine, Chondroitin & MSM is a perfect of blend of essential nutrients for healthy joints. The ingredients help maintain cartilage and reduce inflammation in joints.

Glucosamine, a precursor molecule, is important for maintaining elasticity, strength, and resiliency of the cartilage in articular (movable) joints. The cartilage pad distributes the force of impact across the broad surface of bone and supporting structures, limiting damage to the joint. In addition, cartilage facilitates frictionless gliding of the joint surfaces. Along with supporting cartilage and other connective tissue, glucosamine has anti-inflammatory properties and has been used extensively to promote the maintenance of joint function and to decrease pain in individuals suffering from osteoarthritis. Glucosamine may act synergistically with chondroitin sulfate.

Glucosamine is an amino-sugar that is naturally produced in humans. It is the key substrate used in the synthesis of macromolecules which comprise connective tissue. It is involved in the synthesis of glycolipids, glycoproteins, hyaluronic acid, proteoglycans, and glycosaminoglycans, which are the major structural components of cartilage. In addition to structural support, facilitating production of hyaluronic acid enhances the anti-inflammatory effects of this molecule.

Chondroitin sulfate is a natural physiologic compound and is one of the critical compounds in connective tissue (including vessel walls) and joint cartilage. Chondroitin sulfate absorbs water, adding to the cartilage thickness and its capacity to absorb and distribute compressive forces. The ability of cartilage to compress and expand also facilitates distribution to chondrocytes and tissues adjacent to the cartilage. Supplementation of chondroitin sulfate is claimed to support the maintenance of strong, healthy cartilage and joint function. Chondroitin sulfate inhibits synovial enzymes (elastase, hyaluronidase) which may contribute to cartilage destruction and loss of joint function. Although studies are not conclusive, chondroitin has been reported to act synergistically with glucosamine to support the maintenance of joint cartilage in osteoarthritis.

MSM (Methyl sulfonyl methane, also known as dimethyl sulfone (DMSO2)) is a source of biological sulfur, an important component of proteins, connective tissues, hormones, and enzymes. Hepatic detoxification also requires adequate sulfur stores. MSM is believed to relieve pain by several possible mechanisms. It may inhibit transmission of pain impulses along type C nerve fibers, increase blood flow, and reduce muscular spasm. In addition, MSM appears to act as an anti-inflammatory agent, possibly by limiting the release of inflammatory mediators.